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Ribobay Pharma boosts CRDMO offerings with Cytiva's first FlexFactory platform for oligonucleotides
WTNH-TV New Haven· 7 hours agoRibobay Pharma, a leading Chinese biopharmaceutical contract research, development, and...
BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation -...
Nature· 1 day agoThe N-BAR domain protein BIN1 acts as a scaffolding protein during filopodia formation in myoblast cells, together with identified co-factors.
Uncommon opsin’s retinal isomer is involved in mammalian sperm thermotaxis - Scientific Reports
Nature· 11 hours agoIn recent years it became apparent that, in mammals, rhodopsin and other opsins, known to act as photosensors in the visual system, are also present in spermatozoa, where they function as highly ...
Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF -...
Nature· 3 days agoThis study identifies a unique “internal-PDZ binding motif” (IPM) of WGEF that mediates its interaction with Dvl2PDZ, leading to the release of GEF from its autoinhibitory state. It further unravels the underlying mutual Dvl2-IPM recognition aspects.
Midkine promotes renal fibrosis by stabilizing C/EBPβ to facilitate endothelial-mesenchymal...
Nature· 3 days agoThis study focuses on how endothelial cells contribute to ECM accumulation of renal fibrosis and suggests that MDK promotes ACTA2 expression by stabilizing the C/EBPβ protein.
Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression - Communications...
Nature· 3 days agoPNUTS-deficient mice exhibit multiorgan failure and vascular leakage. PNUTS regulates SEMA3B, suggesting a target for endothelial aging.
Fluorescence imaging sheds light on the immune evasion mechanisms of hepatic stellate cells mediated...
Nature· 11 hours agoUsing two-photon fluorescence imaging, the authors show that superoxide anion in hepatic stellate cells impairs the infiltration of CD8+ T cells in a mouse model of hepatocellular carcinoma.
BIOLASE to Report First Quarter 2024 Results on May 13, 2024
Digital Journal· 4 days agoPRESS RELEASE Published May 6, 2024 ACCESSWIRE LAKE FOREST, CA / ACCESSWIRE / May 6, 2024 / BIOLASE, Inc. (NASDAQ:BIOL), the globally recognized leader in dental laser technology ...
Snakes fake dying using "dripping mouthfuls" of blood
Newsweek· 3 days agoA species of snake that fakes its own death to avoid being being eaten by predators uses some pretty...
A Novel Panic Pathway in the Brain
The Scientist· 11 hours agoEvery year, about 11 percent of Americans experience the heart-pounding, nauseating sensations of intense fear that characterize a panic attack.1 While...