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Life Sciences Company Escapes Criminal Charges for Employee’s Illegal Export Scheme | JD Supra
JD Supra· 3 days agoSigma-Aldrich, Inc., d/b/a MilliporeSigma (“MilliporeSigma”), a U.S. life sciences company based in Massachusetts, escaped criminal charges ...
Salvianolic acid A inhibits ferroptosis and protects against intracerebral hemorrhage - Scientific...
Nature· 2 days agoIntracerebral hemorrhage (ICH) is a common cerebral vascular disease with high incidence, disability, and mortality. Ferroptosis is a regulated type of iron-dependent, non-apoptotic programmed ...
Uncovering kinesin dynamics in neurites with MINFLUX - Communications Biology
Nature· 3 days agoA MINFLUX tracking study of a truncated kinesin-1 mutant in gently fixed primary rat hippocampal neurons revealed 8 nm substeps and a rotation of its head during the unbound state with nanometer/millisecond resolution
University of Florida employee, students implicated in illegal plot to ship drugs, toxins to China
Associated Press· 3 days agoA University of Florida research employee and students have been implicated in an illegal,...
A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits - Nature...
Nature· 3 days agoPdCO is a switchable optogenetic tool for inhibiting synaptic transmission in neuronal terminals in vivo, as demonstrated in a variety of contexts mainly in the mouse.
Assessment of intraocular foreign body using high resolution 3D ultrasound imaging - Scientific...
Nature· 6 days agoOcular trauma often involves intraocular foreign bodies (IOFBs) that pose challenges in accurate diagnosis due to their size, shape, and material composition. In this study, we proposed a novel ...
A novel mutation of DNA2 regulates neuronal cell membrane potential and epileptogenesis - Cell Death...
Nature· 5 days agoMesial temporal lobe epilepsy (MTLE) is one of the most intractable epilepsies. Previously, we reported that mitochondrial DNA deletions were associated with epileptogenesis. While the underlying ...
Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a...
Nature· 4 days agoA biosynthetic gene cluster from a Bacillus strain from the mouse gut produces bacillamide D, a selective cytotoxin, inhibiting growth and motility of human cell lines and murine organoids in vitro.
Population-based nanopore sequencing of the HIV-1 pangenome to identify drug resistance mutations -...
Nature· 5 days agoHIV-1 drug resistance genotypic tests have primarily been performed by Sanger sequencing of gene segments encoding different drug target proteins. Since the number of targets has increased with ...