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Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in...
Nature· 6 hours agoFor each filter plate, mRNA was extracted using the Dynabeads mRNA DIRT Purification Kit (cat. Cells were lysed using glass beads and lysis buffer, then incubated for 2 min at 65 °C. After RNA ...
How Migrating Cells Navigate Biological Mazes
The Scientist· 6 days agoA key protein that detects changes in plasma membrane curvature guides immune-like cells through environmental obstacles.
Ancient viral DNA in the human genome linked to major psychiatric disorders
Medical Xpress· 4 hours agoNew research led by King's College London has found that thousands of DNA sequences originating from...
Liver ACOX1 regulates levels of circulating lipids that promote metabolic health through adipose...
Nature· 5 days agoThe peroxisomal β-oxidation enzyme ACOX1 increases in liver with obesity, but the physiological significance is unclear. Here, the authors show that liver-specific knockout of Acox1 leads to ...
TRIM45 facilitates NASH-progressed HCC by promoting fatty acid synthesis via catalyzing FABP5...
Nature· 6 days agoWe found TRIM45 exacerbates HCC cells proliferation and metastasis in vitro and in vivo. Further transcriptome analysis revealed TRIM45 predominantly affects fatty acid metabolism ...
Anticancer potential of CLK kinase inhibitors 1C8 and GPS167 via EMT and antiviral immune response
Medical Xpress· 2 days agoA new research paper titled "The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response" has been published in Oncotarget.
Multiomic analyses uncover immune system response to a heart attack
Medical Xpress· 23 hours agoResearchers at LMU University Hospital, Helmholtz Munich and other institutions have now used high-tech biomedical and bioinformatics methods to comprehensively map the immune response to myocardial ...
NeuroBo Pharmaceuticals' DA-1241 in Combination with Semaglutide Improves Liver Fibrosis and...
WRBL Columbus· 1 hour agoNeuroBo Pharmaceuticals, Inc. (Nasdaq: NRBO), a clinical-stage biotechnology company focused on the transformation of cardiometabolic diseases, today announced that pre-clinical data suggests ...
New research suggests diverse headgear in hoofed mammals evolved from common ancestor
Phys.org· 2 days agoThis finding is published today in the journal Communications Biology by researchers from the...
Q1 2024 Predictive Oncology Inc Earnings Call
Thomson Reuters StreetEvents via Yahoo Finance· 6 days agoFor those interested in learning more, the first joint webinar will be held on Wednesday, May 29 at 10 AM Eastern Time. Endo toxins, also known as micro polysaccharides LPS are components of ...
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