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Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies
Medical Xpress· 4 hours agoResearchers from the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim...
Valley Children's Receives Historic $15 Million Gift to Create Advanced Cell Therapy Program for...
KTLA-TV Los Angeles· 3 hours agoValley Children's Healthcare this week announced a historic donation of $15 million that will significantly enhance the hospital's ability to provide the most advanced bone marrow transplant ...
Revolutionizing Cancer Treatment: Key to Prolonging CAR T Cell Life Uncovered
SciTechDaily· 4 days agoFOXO1 is required for T cell memory and is linked to longer-lasting clinical outcomes in CAR T cell...
Valley Children’s gets $15M anonymous donation
CBS 47 Fresno· 53 minutes agoMADERA, Calif. (KSEE/KGPE) – An anonymous benefactor has given a $15 million donation to Valley Children’s Hospital, funds that staff say will...
Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets
Medical Xpress· 5 hours agoSt. Jude Children's Research Hospital scientists have identified 156 potential targets through a...
New technique improves T cell-based immunotherapies for solid tumors
Medical Xpress· 2 days agoScientists from Scripps Research have enhanced an existing immunotherapy by removing the sugar coating surrounding solid tumors—such as in melanoma, breast, and prostate cancer—so T cells can ...
Turning a tumor's 'shield' into a weapon against itself
Medical Xpress· 1 day agoWang, the Chair of the Alfred E. Mann Department of Biomedical Engineering and the Dwight C. and...
Targeting myeloma essential genes using NOT Gated CAR T-cells, a computational approach - Leukemia
Nature· 4 days agoChimeric antigen receptor (CAR) T-cells have recently been demonstrated to be highly effective in the disease, but the survival curves are yet to plateau. Thus, on-target, off-tumour toxicity ...
Replay wins IND clearance for PRAME T cell cancer therapy
Pharmaceutical Technology via Yahoo Finance· 2 days agoGenome writing company Replay Bio has had its investigational new drug (IND) application cleared by...
Earnings call: TG Therapeutics sees strong Q1 growth with Briumvi By Investing.com
Investing.com· 8 hours agoThe company announced that Briumvi's US revenue surpassed $50 million, contributing to total...