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In a 1st, HIV vaccine triggers rare and elusive antibodies in human patients
Live Science via Yahoo News· 6 days ago"We're having to coax the immune system, to guide the immune system in a way we've never had to do."...
Muscular dystrophy prevention, outlook, and slowing progression
Medical News Today· 4 days agoA person may inherit the genetic changes responsible for muscular dystrophy. Muscular dystrophies...
Impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a computational approach...
Nature· 2 days agoA computational modeling study indicates that relative amount and timing of Ebola virus proteins VP40 and NP drive effective viral particle production.
PKMYT1, a potential 'Achilles heel' of treatment resistant ER+ breast cancers with the poorest...
Medical Xpress· 3 days agoLooking to identify new vulnerabilities in this type of cancer that could lead to improved...
Repurposed protease controls important signaling molecule-activating protein
Phys.org· 5 days agoThis process involves ADAM17 cleaving (shedding) the signaling molecules from their precursor forms...
Intravenous Immunoglobulin (IVIG) Therapy: How It Works and What to Expect
Verywell Health via Yahoo News· 6 days agoIntravenous Immunoglobulin (IVIG) therapy is a biologic treatment used for immunodeficiencies,...
Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive...
Nature· 4 days agoPlectasin, a natural host defence peptide of fungal origin, uses a calcium-sensitive supramolecular killing mechanism to block bacterial cell wall synthesis.
IGF2BP2-modified circular RNA circCHD7 promotes endometrial cancer progression via stabilizing...
Nature· 5 days agoFunctionally, circCHD7 was found to promote the proliferation of EC cells. Mechanistically, circCHD7 interacted with insulin-like growth factor 2 mRNA-binding protein (IGF2BP2 ...
Universal LIPSTIC: a new tool for decoding cellular interactions - Nature Reviews Immunology
Nature· 4 days agoIt is through these interactions that cells share information, shaping each other’s function. In 2018, our group introduced LIPSTIC (labelling immune partnerships by Sor-tagging intercellular ...
Recognition of antiepileptic brivaracetam by synaptic vesicle protein 2A - Cell Discovery
Nature· 6 days agoDear Editor,Epilepsy is the most prevalent chronic brain illness that strikes ~70 million people of all ages worldwide, causing a wide range of neurobiological, cognitive, and psychosocial consequences, with infants and the elderly