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Unlocking Reversible Male Contraception – New Research Suggests a Revolutionary Approach to...
SciTechDaily· 11 hours agoA new study reveals that targeting the STK33 protein can induce safe, reversible infertility in male mice, offering hope for nonhormonal male contraceptives. Researchers have discovered that ...
ASCO 2024: Verastem’s combo therapy for pancreatic cancer hits early trial success
Clinical Trials Arena via Yahoo Finance· 7 days agoVerastem Oncology reported positive initial results from an ongoing Phase I/II trial investigating ...
InxMed Reports Positive Phase Ib/II Results for Ifebemtinib in Combination with Garsorasib in...
WKBN 27 Youngstown· 18 hours agoIfebemtinib in combination with garsorasib in NSCLC showed ORR of 90.3% and DCR of 96.8% Ifebemtinib is a highly selective, orally administered, focal adhesion kinase inhibitor ...
Phosphorylation of caspase-8 by RSKs via organ-constrained effects controls the sensitivity to...
Nature· 7 days agoCaspase-8 (Casp8) serves as an initiator of apoptosis or a suppressor of necroptosis in context-dependent manner. Members of the p90 RSK family can phosphorylate caspase-8 at threonine-265 ( ...
BerGenBio First Quarter Results 2024: Advancing to the Next Stage of Development
WROC Rochester· 2 days agoBerGenBio ASA (OSE: BGBIO), a clinical-stage bio-pharmaceutical company developing novel, selective...
New research moves closer to male birth control pill
United Press International via Yahoo News· 7 days agoFor decades, the responsibility for birth control has fallen largely on women, but new research suggests a birth control pill for men might one day...
Exelixis (EXEL) Down 6.6% Since Last Earnings Report: Can It Rebound?
Zacks via Yahoo Finance· 12 hours agoA filing for this indication in the United States is also targeted in 2024. Exelixis plans to...
Upregulation of rate-limiting enzymes in cholesterol metabolism by PKCδ mediates endothelial...
Nature· 2 days agoIt is characterized by heightened endothelial apoptosis and impaired angiogenesis. In this study, we aimed to investigate the role of protein kinase Cδ (PKCδ) in regulating ...
PKMYT1, a potential 'Achilles heel' of treatment resistant ER+ breast cancers with the poorest...
Medical Xpress· 6 days agoSpecifically, they searched for enzymes called kinases, whose expression is typically altered in...
Discovery by VCU researchers could ‘move the field forward’ for breast cancer treatment
WRIC 8 News Richmond· 7 hours agoResearchers at the Virginia Commonwealth University (VCU) Massey Comprehensive Cancer Center have...