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Double lung transplants weren’t typically recommended for lung cancer patients. But a new technique...
San Jose Mercury News· 1 day agoFor decades, double lung transplants were not considered a viable option for treating lung cancer....
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous...
Nature· 6 days agoE7820 and Indisulam (E7070) are sulfonamide molecular glues that modulate RNA splicing by degrading the splicing factor RBM39 via ternary complex formation with the E3 ligase adaptor DCAF15.
A negative feedback loop underlies the Warburg effect - npj Systems Biology and Applications
Nature· 6 days agoAerobic glycolysis, or the Warburg effect, is used by cancer cells for proliferation while producing lactate. Although lactate production has wide implications for cancer progression, it is ...
For some endometriosis-related ovarian cancers, timing is everything
Medical Xpress· 1 day agoThe findings, published in the journal Cancer Research, have implications for better understanding and treating a pair of cancer subtypes that together account for up to nearly a quarter of ...
Across the Entire Tree of Life – “Cell Cannibalism” Is Much More Common Than Scientists Thought
SciTechDaily· 6 days agoNew research reveals that cell-in-cell phenomena, where one cell consumes another, are common across...
ASCO 2024: Rakuten’s photoimmunotherapy and Keytruda combo shows efficacy in HNSCC
Clinical Trials Arena via Yahoo Finance· 1 day agoUS-based Rakuten Medical has announced positive interim data from the Phase Ib/II trial of its...
All the Details on Princess Kate’s Health Status and Whereabouts
Harper's Bazaar via Yahoo News· 1 day agoAll About Princess Kate’s Cancer DiagnosisMax Mumby/Indigo - Getty Images Catherine, the Princess of...
'My daughter only ate Yorkshire puddings every day for 7 years until we tried hypnosis'
Yahoo Life UK· 14 hours agoTallulah Dent resorted to hypnosis to stop her Yorkshire pudding addiction. (SWNS) A young girl who...
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis...
Nature· 3 days agoCancer stem cells (CSCs) are a sub-population of cells possessing high tumorigenic potential, which contribute to therapeutic resistance, metastasis and recurrence. Eradication of CSCs is widely ...
KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid...
Nature· 6 days agoInactivated suppressor of mothers against decapentaplegic homolog (SMAD) 4 significantly affects cancer development in pancreatic ductal adenocarcinoma (PDAC). However, the contribution of smad4 ...