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Convergent evolution of fern nectaries facilitated independent recruitment of ant-bodyguards from...
Nature· 4 days agoSome plants use nectar to attract ant bodyguards. Here, the authors use a cross-kingdom phylogenetic approach to find that ferns and angiosperms evolved nectaries in the Cretaceous, coinciding ...
Melatonin alleviates septic ARDS by inhibiting NCOA4-mediated ferritinophagy in alveolar macrophages...
Nature· 4 days agoFerroptosis is a novel form of programmed cell death which can exacerbate lung injury in septic acute respiratory distress syndrome (ARDS). Alveolar macrophages, crucial innate immune cells, ...
MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy - Cell Death &...
Nature· 5 days agoThe pseudokinase mixed lineage kinase domain-like (MLKL) is an essential component of the activation of the necroptotic pathway. Emerging evidence suggests that MLKL plays a key role in liver ...
Foldamers controlled by functional triamino acids: structural investigation of α/γ-hybrid...
Nature· 3 days agoPeptide-like foldamers are known to be controlled by amide backbone hydrogen bonding, however, the influence of functional groups forming individual hydrogen-bond networks remains underexplored ...
Researcher parents are paying a high price for conference travel — here’s how to fix it
Nature· 1 day agoThree scientist mothers call for a change in how conference childcare costs are reimbursed, drawing...
Expanding the phenotypic spectrum of NOTCH1 variants: clinical manifestations in families with...
Nature· 6 days agoPathogenic variants in NOTCH1 are associated with non-syndromic congenital heart disease (CHD) and Adams–Oliver syndrome (AOS). The clinical presentation of individuals with damaging NOTCH1 ...
Rosacea is strongly associated with melanoma in Caucasians - Scientific Reports
Nature· 3 days agoRosacea is often considered a cosmetic problem but is known to be associated with a variety of comorbidities. To identify such risks, we generated two age- and sex-matched real-world cohorts ...
In vitro generation of genetic diversity for directed evolution by error-prone artificial DNA...
Nature· 4 days agoError-prone artificial DNA synthesis (epADS) is presented as an effective method for in vitro generation of genetic diversity for directed evolution of various types of genetic parts, synthetic gene circuits and even microbes.
ADA2 regulates inflammation and hematopoietic stem cell emergence via the A2bR pathway in zebrafish...
Nature· 6 days agoA DADA2 zebrafish model with cecr1b deficiency was generated. Characterization of hematopoietic processes revealed a role of Cecr1b in regulating inflammation and hematopoietic stem cell production through the A2br-mediated adenosine signaling.
Multidrug-resistant Escherichia coli causing canine pyometra and urinary tract infections are...
Nature· 4 days agoDespite extensive characterisation of uropathogenic Escherichia coli (UPEC) causing urinary tract infections (UTIs), the genetic background of non-urinary extraintestinal pathogenic E. coli ...