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A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous...
Nature· 3 days agoTranscriptomic analyses revealed that E7820 treatment resulted in the intron retention of mRNAs and decreased transcription, especially for HRR genes. This induced HRR malfunction ...
Ipilimumab, a Pioneer Breakthrough in Cancer Treatment
Forbes· 7 days agoIn 2011, the first in a new generation of anticancer drugs called checkpoint inhibitors was...
Alligator Bioscience To Present Positive Phase 2 Mitazalimab Data in Pancreatic Cancer at 2024 ASCO...
Morningstar· 3 days agoOPTIMIZE-1 study results showed confirmed ORR of 40.4%, unconfirmed ORR of 50.9% and DCR of 79% in 57 evaluable patients with chemotherapy-naïve mPDACThe encouraging duration of response (median ...
AI + navigation = faster cancer care at Northwell
Becker’s Hospital Review· 3 days agoNew York City-based Northwell Health has reduced the number of days that pancreatic cancer patients wait until they receive a biopsy, oncology visit and ...
Verastem (VSTM) Up on Upbeat Early Pancreatic Cancer Study Data
Zacks· 3 days agoBoth avutometinib and defactinib have been in-licensed by Verastem from other pharmaceutical...
KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid...
Nature· 3 days agoUpregulated KDM5B promotes PDAC tumor malignancy, i.e. cancer cells stemness and drug resistance in vitro and in vivo, while KDM5B knockout exerts opposite effects. Mechanistically ...
Exercise, therapy and diet can all improve life during cancer treatment and boost survival. Here’s...
The Conversation· 6 days agoWith so many high-profile people diagnosed with cancer we are confronted with the stark reality the disease can strike any of us at any time. There are also reports certain ...
King Charles Feels ‘Responsibility’ to the Public Even ‘When He’s Not Feeling 100 Percent’
In Touch Weekly via Yahoo News· 2 days agoEver the epitome of the British “stiff upper lip,” King Charles III has been uncomplaining as he...
Genetic cancer screening: Learning more about lesser known hereditary cancers
WTAE Pittsburgh· 6 days agoAccording to the National Cancer Institute, these inherited variants are thought to contribute to...
Why Is Verastem (VSTM) Stock Down 62% Today?
InvestorPlace· 2 days agoVerastem (NASDAQ:VSTM) stock is falling hard on Friday following the release of new clinical trial data for its metastatic pancreatic cancer treatment...