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Agricultural drought-driven mechanism of coupled climate and human activities in the karst basin of...
Nature· 4 days agoTimely and accurate agricultural drought monitoring and drought-driven mechanism analysis in karst basins in the context of global warming are highly important for drought disaster monitoring ...
Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA...
Nature· 3 days agoAn epitope binning platform based on mammalian cell surface display and DNA sequencing enables the simultaneous binning of multiple antibodies without the need for antibody production and purification.
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis...
Nature· 4 days agoCancer stem cells (CSCs) are a sub-population of cells possessing high tumorigenic potential, which contribute to therapeutic resistance, metastasis and recurrence. Eradication of CSCs is widely ...
A successional shift enhances stability in ant symbiont communities - Communications Biology
Nature· 4 days agoAs red wood ant nests age, the arthropod symbiont communities they support undergo a successional shift. This change is marked by a greater degree of specialization and evenness within the community, resulting in increased community stability.
Rosacea is strongly associated with melanoma in Caucasians - Scientific Reports
Nature· 6 days agoRosacea is often considered a cosmetic problem but is known to be associated with a variety of comorbidities. To identify such risks, we generated two age- and sex-matched real-world cohorts ...
Exploring the pathways of drug repurposing and Panax ginseng treatment mechanisms in chronic heart...
Nature· 4 days agoChronic Heart Failure (CHF) is a significant global public health issue, with high mortality and morbidity rates and associated costs. Disease modules, which are collections of disease-related ...
Hsa_circ_0007590/PTBP1 complex reprograms glucose metabolism by reducing the stability of...
Nature· 4 days agoThe role of circular RNAs (circRNAs) in glucose metabolism in pancreatic duct adenocarcinoma (PDAC) remains elusive. Through RNA sequencing of cells cultured under conditions of glucose deprivation ...
Multidimensional primate niche space sheds light on interspecific competition in primate evolution -...
Nature· 4 days ago7-dimensional niche space of 191 primate species shows niche diversity is partitioned unequally. Interspecific competition is lowest in great apes and highest in callitrichids.
Advances in highly targeted radiation treatment for cancer have ignited interest in a once obscure...
Nature· 2 days agoTherapies that treat while diagnosing — theranostics — can extend length of survival and improve the...
How antibody–drug conjugates aim to take down cancer
Nature· 2 days agoScientists are trying to work out how to balance potency with toxicity and tackle the cost of next-generation therapeutics.