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Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis...
Nature· 16 hours agoHere, we show that the lysosomal cation channel TRPML1 represents a promising target for CSCs. TRPML1 is highly expressed in breast cancer cells and exhibits ...
Mirat Shah, MD, on Elacestrant's FDA Approval for Breast Cancer With ESR1 Mutations
MedPage Today· 6 days agoFDA scientists published a detailed rationale for the approval of elacestrant (Orserdu), the first...
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous...
Nature· 4 days agoExome sequencing of the PDX genome revealed that loss-of-function mutations in genes of the homologous recombination repair (HRR) system, such as ATM, were...BRCA1/2 transcripts ...
Anti-Cancer Drug Pembrolizumab: Frequently Used Alone Or With Other Treatments
Forbes· 18 hours agoPembrolizumab, sold as Keytruda by Merck & Co., was one of the first inhibitors to hit the market. A...
Edgewood Oncology treats first two subjects in breast cancer trial
Clinical Trials Arena via Yahoo Finance· 5 days ago“Moreover, while CDK4/6 inhibitors...resistance to these therapies poses a formidable challenge. By...
KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid...
Nature· 4 days agoInactivated suppressor of mothers against decapentaplegic homolog (SMAD) 4 significantly affects cancer development in pancreatic ductal adenocarcinoma (PDAC). However, the ...
Summer is here! Your need-to-know sunscreen guide
KHON 2 Honolulu· 6 hours agoIt’s National Sunscreen Day, and it’s the unofficial start to summer. So, KHON2.com decided to give you a few pointers on how to select sunscreens for...
Eisai Showcases Oncology Portfolio and Pipeline at ASCO 2024
FOX 23 News Albany· 4 days agoEisai announced today the presentation of research across multiple types of cancer from its oncology portfolio and pipeline during the 2024 American Society of Clinical Oncology ...
Can This Well-Loved Herb Help Fight Malignancies?
Mercola· 5 days agoStudies2,3,4 also support the notion that this humble herb has anticancer effects, which should be good enough reason for you to include more of it in your diet. A study published in Biomedicine ...
Rutgers Cancer Institute and RWJBarnabas Health Se | Newswise
Newswise· 5 days agoClinicians and scientists from Rutgers Cancer Institute and RWJBarnabas Health will lead sessions...
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