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Convergent evolution of fern nectaries facilitated independent recruitment of ant-bodyguards from...
Nature· 11 hours agoSome plants use nectar to attract ant bodyguards. Here, the authors use a cross-kingdom phylogenetic approach to find that ferns and angiosperms evolved nectaries in the Cretaceous, coinciding ...
Multidrug-resistant Escherichia coli causing canine pyometra and urinary tract infections are...
Nature· 11 hours agoDespite extensive characterisation of uropathogenic Escherichia coli (UPEC) causing urinary tract infections (UTIs), the genetic background of non-urinary extraintestinal pathogenic E. coli ...
Induced dual-target rebalance simultaneously enhances efficient therapeutical efficacy in tumors -...
Nature· 1 day agoMultiple gene abnormalities are major drivers of tumorigenesis. NF-κB p65 overactivation and cGAS silencing are important triggers and genetic defects that accelerate tumorigenesis. However, ...
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury - Communications...
Nature· 1 day agoActivation of the Nrf2/HO-1 antioxidant signaling pathway exacerbates cholestatic liver injury due to excessive accumulation of bilirubin, rather than exerting a protective effect as in non-cholestatic liver injury.
Lab-grown sperm and eggs: ‘epigenetic’ reset in human cells paves the way
Nature· 4 days agoTechnique wipes away tags on DNA that must be reprogrammed during development of reproductive cells.
Software tools identify forgotten genes
Nature· 11 hours agoFind My Understudied Genes and the Unknome database highlight interesting genes that have been neglected by science.
Ozempic keeps wowing: trial data show benefits for kidney disease
Nature· 18 hours agoSemaglutide, the same compound in obesity drug Wegovy, slashes risk of kidney failure and death for...
MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy - Cell Death &...
Nature· 1 day agoThe pseudokinase mixed lineage kinase domain-like (MLKL) is an essential component of the activation of the necroptotic pathway. Emerging evidence suggests that MLKL plays a key role in liver ...
Survival dynamics of starving bacteria are determined by ion homeostasis that maintains plasmolysis...
Nature· 1 day agoWhen bacteria starve, their cytoplasm detaches from the cell wall. A model now shows that this process determines bacterial death rates and can be controlled to keep bacteria viable in a starved state.
Flicker electroretinogram in preterm infants - Eye
Nature· 1 day agoInfants born prematurely are at risk of developing retinopathy of prematurity, which is associated with abnormalities in retinal function as measured using electroretinography. The aim of this ...