Search results
Decidual natural killer cells dysfunction is caused by IDO downregulation in dMDSCs with Toxoplasma...
Nature· 9 hours agoIDO downregulation in dMDSCs induced by Toxoplasma gondii infection regulates expression of TGF-β and IL-10 through the Kyn/AhR/SP1 signal pathway, eventually contributing to the dysfunction of dNK cells.
Maternal behaviours disrupted by Gprasp2 deletion modulate neurodevelopmental trajectory in progeny...
Nature· 13 hours agoAutism spectrum disorders (ASDs) are known to present sex-specific differences. At the same time, understanding how maternal behaviours are affected by pathogenic mutations is crucial to translate ...
Antidepressant-induced membrane trafficking regulates blood-brain barrier permeability - Molecular...
Nature· 1 day agoAs the most prescribed psychotropic drugs in current medical practice, antidepressant drugs (ADs) of the selective serotonin reuptake inhibitor (SSRI) class represent prime candidates for drug ...
Biggest genome ever found belongs to this odd little plant
Nature· 16 hours agoThe gigantic genome of a type of fork fern smashes the human one in terms of size.
Detection of inflammasome activation in liver tissue during the donation process as potential...
Nature· 1 day agoDeceased donor liver transplantation (LT) is a crucial lifesaving option for patients with end-stage liver diseases. Although donation after brain death (DBD) remains the main source of donated ...
Single cell RNA analysis uncovers the cell differentiation and functionalization for air breathing...
Nature· 1 day agoSingle-cell atlas of Microhyla fissipes lungs reveals cell differentiation and functionalization during metamorphosis, further cross-species comparison sheds light vertebrate lung cell type evolution.
Reduced precipitation can induce ecosystem regime shifts in lakes by increasing internal nutrient...
Nature· 1 day agoEutrophication is a main threat to continental aquatic ecosystems. Prevention and amelioration actions have been taken under the assumption of a stable climate, which needs reconsideration.
The cicadas are here! Why US researchers are swarming to study them
Nature· 16 hours agoTwo particular broods of the insects are popping up together for the first time in two centuries,...
Oncofetal SNRPE promotes HCC tumorigenesis by regulating the FGFR4 expression through alternative...
Nature· 6 days agoDue to insufficient knowledge about key molecular events, Hepatocellular carcinoma (HCC) lacks effective treatment targets. Spliceosome-related genes were significantly altered in HCC. Oncofetal ...
Neural correlates of obesity across the lifespan - Communications Biology
Nature· 3 days agoThis study reveals that obesity-related brain changes evolve across the lifespan and involve mitochondrial and inflammatory genes, as well as neurochemical and cognitive alterations.