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Oncofetal SNRPE promotes HCC tumorigenesis by regulating the FGFR4 expression through alternative...
Nature· 19 hours agoDue to insufficient knowledge about key molecular events, Hepatocellular carcinoma (HCC) lacks effective treatment targets. Spliceosome-related genes were significantly altered in HCC. Oncofetal ...
Higher surface folding of the human premotor cortex is associated with better long-term learning...
Nature· 19 hours agoA brain imaging study shows that humans with more complex cortical folds in a premotor brain region have a higher capacity to learn a challenging new motor skill during six weeks of practice.
Bio-stimulating effect of endophytic Aspergillus flavus AUMC 16068 and its respective...
Nature· 19 hours agoHeavy metal accumulation is one of the major agronomic challenges that has seriously threatened food safety. As a result, metal-induced phytotoxicity concerns require quick and urgent action ...
Palladium doped PDA-coated hercynite as a highly efficient catalyst for mild hydrogenation of...
Nature· 19 hours agoHercynite magnetic nanoparticles were produced through the co-precipitation of ferrous and aluminum cations. The surface of hercynite was respectively coated with silica, 2,4,6-trichloro-1,3,5 ...
Modulating water hydrogen bonding within a non-aqueous environment controls its reactivity in...
Nature· 2 days agoElectroreduction of CO2 competes with the hydrogen evolution reaction; thus, controlling water’s activity to exclusively act as a proton donor is a desirable yet challenging goal. Now the behaviour ...
Rosacea is strongly associated with melanoma in Caucasians - Scientific Reports
Nature· 19 hours agoRosacea is often considered a cosmetic problem but is known to be associated with a variety of comorbidities. To identify such risks, we generated two age- and sex-matched real-world cohorts ...
A DNA demethylase reduces seed size by decreasing the DNA methylation of AT-rich transposable...
Nature· 5 days agoA study on a soybean DNA demethylase reveals that seed size is negatively regulated by GmDMEa, which is closely linked to methylation on transposon elements.
p52-ZER6/IGF1R axis maintains cancer stem cell population to promote cancer progression by enhancing...
Nature· 5 days agoCancer stem cells (CSCs), which are distinct subpopulations of tumor cells, have a substantially higher tumor-initiating capacity and are closely related to poor clinical outcomes. Damage to ...
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury - Communications...
Nature· 3 days agoActivation of the Nrf2/HO-1 antioxidant signaling pathway exacerbates cholestatic liver injury due to excessive accumulation of bilirubin, rather than exerting a protective effect as in non-cholestatic liver injury.
GDE5/Gpcpd1 activity determines phosphatidylcholine composition in skeletal muscle and regulates...
Nature· 6 days agoSkeletal muscle-specific GDE5/Gpcpd1 deletion leads to glycerophosphocholine accumulation, which alters skeletal muscle phospholipid profiles and reduces passive force in electrically stimulated skeletal muscles in vivo.