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Protein arginine methyltransferase 2 controls inflammatory signaling in acute myeloid leukemia -...
Nature· 19 hours agoPRMT2 is a key regulator of inflammation in acute myeloid leukemia. PRMT2-deficient cells exhibit a pro-inflammatory profile associated with STAT3 activation.
Why museums should repatriate fossils
Nature· 3 days agoThe legacy of a palaeontology expedition into Native American lands 150 years ago should prompt a rethink of where and how fossil collections are...
Exploring mesoscopic mass transport effects on electrocatalytic selectivity - Nature Catalysis
Nature· 7 days agoMesoscopic mass transport is often ignored but it can influence electrocatalytic processes. This Analysis introduces a simple multi-scale model that couples diffusion to electrochemical surface ...
Gut microbiome discovery provides roadmap for life-saving cancer therapies
Nature· 1 day agoThe balance between bacterial communities in the gut affects the likelihood of a positive response...
Direct radical functionalization of native sugars - Nature
Nature· 2 days agoA radical-based method for functionalizing native sugars shows a way to remove typical protecting-group manipulations.
Progressive senescence programs induce intrinsic vulnerability to aging-related female breast cancer...
Nature· 4 days agoAging-related cancer incidence remains not fully understood. Here, the authors depict a progressive process of senescence in murine mammary stem cells at single-cell resolution, which is governed ...
How germ granules promote germ cell fate - Nature Reviews Genetics
Nature· 3 days agoIn this Review, Pamula and Lehmann describe how distinct membraneless germ granules organize the germ cell cytoplasm at different stages of the germline life cycle to determine germ cell identity ...
Integrative analysis of single-cell RNA-seq and gut microbiome metabarcoding data elucidates...
Nature· 6 days agoChronic ulcerative colitis in mice is characterized by pro-inflammatory M1 macrophage phenotype and higher Nampt and NOX2 transcription, as well as a reduced taxonomic diversity in the mice gut microbiome.
Ceftazidime is a potential drug to inhibit cell proliferation by increasing cellular p27 - The...
Nature· 2 days agoThe development of new therapeutic uses for existing drugs is important for the treatment of some diseases. Cephalosporin antibiotics stand as the most extensively utilized antibiotics in clinical ...
Could rats and dogs detect disease better than the finest lab equipment?
Nature· 2 days agoThe animals’ keen sense of smell could improve the detection of illnesses such as cancer and...