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Reduced precipitation can induce ecosystem regime shifts in lakes by increasing internal nutrient...
Nature· 3 hours agoEutrophication is a main threat to continental aquatic ecosystems. Prevention and amelioration actions have been taken under the assumption of a stable climate, which needs reconsideration.
Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel...
Nature· 1 day agoCerebral small vessel disease (cSVD) is a leading cause of stroke and dementia. Genetic risk loci for white matter hyperintensities (WMH), the most common MRI-marker of cSVD in older age, were ...
Unlocking bacterial potential to reduce farmland N2O emissions - Nature
Nature· 1 day agoA study presents a method to mitigate emissions of nitrous oxide from farmland using bacteria to consume nitrous oxide in soil with organic waste as a substrate and vector.
Transgene removal using an in cis programmed homing endonuclease via single-strand annealing in the...
Nature· 1 day agoThis study demonstrates that inserted transgene sequences in the Aedes aegypti genome can be pre-programmed to remove themselves and restore a formerly disrupted target gene through the in cis activity of homing endonucleases.
DRAIC mediates hnRNPA2B1 stability and m6A-modified IGF1R instability to inhibit tumor progression -...
Nature· 1 day agoType 1 insulin-like growth factor receptor (IGF1R) plays an important role in cancer, however, posttranscriptional regulation such as N6-methyladenosine (m6A) of IGF1R remains unclear. Here, ...
Fasting alleviates metabolic alterations in mice with propionyl-CoA carboxylase deficiency due to...
Nature· 1 day agoDespite prior concerns regarding potential adverse effects, a 23-h fasting regimen mitigates metabolic abnormalities observed in Pcca-mutated mice by reducing propionate production from the ...
Multiple environmental stressors affect predation pressure in a tropical freshwater system -...
Nature· 1 day agoField observations show that fish predators exhibit stronger association with warmer, still, clear waters. Here they exert heightened predation pressure on prey fish, highlighting the importance of ecological context in predator-prey dynamics.
Upregulation of rate-limiting enzymes in cholesterol metabolism by PKCĪ“ mediates endothelial...
Nature· 1 day agoDiabetic foot ulcer (DFU) is a prevalent complication of diabetes that poses significant challenges in terms of treatment and management. It is characterized by heightened endothelial apoptosis ...
Oncofetal SNRPE promotes HCC tumorigenesis by regulating the FGFR4 expression through alternative...
Nature· 5 days agoDue to insufficient knowledge about key molecular events, Hepatocellular carcinoma (HCC) lacks effective treatment targets. Spliceosome-related genes were significantly altered in HCC. Oncofetal ...
Retraction Note: CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7 - Cell...
Nature· 1 day agoRetraction to: Cell