Search results
Multi-wall carbon Nanotube surface-based functional nanoparticles for stimuli-responsive dual...
Nature· 2 days agoCarbon nanotubes (CNTs) have the potential to serve as delivery systems for medicinal substances and gene treatments, particularly in cancer treatment. Co-delivery of curcumin (CUR) and Methotrexate ...
Neural correlates of obesity across the lifespan - Communications Biology
Nature· 1 day agoThis study reveals that obesity-related brain changes evolve across the lifespan and involve mitochondrial and inflammatory genes, as well as neurochemical and cognitive alterations.
Flicker electroretinogram in preterm infants - Eye
Nature· 6 days agoInfants born prematurely are at risk of developing retinopathy of prematurity, which is associated with abnormalities in retinal function as measured using electroretinography. The aim of this ...
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury - Communications...
Nature· 6 days agoActivation of the Nrf2/HO-1 antioxidant signaling pathway exacerbates cholestatic liver injury due to excessive accumulation of bilirubin, rather than exerting a protective effect as in non-cholestatic liver injury.
In vivo cyclic overexpression of Yamanaka factors restricted to neurons reverses age-associated...
Nature· 5 days agoPartially reprogramming a specific population of neurons in the cerebral cortex of mice, improves cognition through greater activation in memory circuits and plasticity induced by the reorganization of the extracellular matrix.
Microbial polyphenol metabolism is part of the thawing permafrost carbon cycle - Nature Microbiology
Nature· 1 day agoDiverse microbial polyphenol transformations in thawing permafrost refute the theory that these compounds stabilize soil carbon across Arctic landscapes.
Mitochondrial calcium uniporter promotes kidney aging in mice through inducing mitochondrial...
Nature· 5 days agoRenal tubular epithelial cell senescence plays a critical role in promoting and accelerating kidney aging and age-related renal fibrosis. Senescent cells not only lose their self-repair ability ...
Modulating water hydrogen bonding within a non-aqueous environment controls its reactivity in...
Nature· 5 days agoElectroreduction of CO2 competes with the hydrogen evolution reaction; thus, controlling water’s activity to exclusively act as a proton donor is a desirable yet challenging goal. Now the behaviour ...
Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA...
Nature· 1 day agoAn epitope binning platform based on mammalian cell surface display and DNA sequencing enables the simultaneous binning of multiple antibodies without the need for antibody production and purification.
Induced dual-target rebalance simultaneously enhances efficient therapeutical efficacy in tumors -...
Nature· 6 days agoMultiple gene abnormalities are major drivers of tumorigenesis. NF-κB p65 overactivation and cGAS silencing are important triggers and genetic defects that accelerate tumorigenesis. However, ...