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Multidrug-resistant Escherichia coli causing canine pyometra and urinary tract infections are...
Nature· 17 hours agoDespite extensive characterisation of uropathogenic Escherichia coli (UPEC) causing urinary tract infections (UTIs), the genetic background of non-urinary extraintestinal pathogenic E. coli ...
Convergent evolution of fern nectaries facilitated independent recruitment of ant-bodyguards from...
Nature· 17 hours agoSome plants use nectar to attract ant bodyguards. Here, the authors use a cross-kingdom phylogenetic approach to find that ferns and angiosperms evolved nectaries in the Cretaceous, coinciding ...
Software tools identify forgotten genes
Nature· 17 hours agoFind My Understudied Genes and the Unknome database highlight interesting genes that have been neglected by science.
Large anomalous Hall conductivity induced by spin chirality fluctuation in an ultraclean frustrated...
Nature· 4 days agoMagnetic frustration of spins often leads to nontrivial spin textures and anomalous Hall responses, but typically below the magnetic transition temperature. The authors observe a giant unconventional ...
Lab-grown sperm and eggs: ‘epigenetic’ reset in human cells paves the way
Nature· 4 days agoTechnique wipes away tags on DNA that must be reprogrammed during development of reproductive cells.
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury - Communications...
Nature· 2 days agoActivation of the Nrf2/HO-1 antioxidant signaling pathway exacerbates cholestatic liver injury due to excessive accumulation of bilirubin, rather than exerting a protective effect as in non-cholestatic liver injury.
TBC9, an essential TBC-domain protein, regulates early vesicular transport and IMC formation in...
Nature· 7 days agoA study suggests that TBC9, one of the Rab GTPase Activating Proteins, is crucial for early vesicular transport and inner membrane complex formation by regulating Rab2, Rab11A and Rab11B in Toxoplasma gondii.
Induced dual-target rebalance simultaneously enhances efficient therapeutical efficacy in tumors -...
Nature· 2 days agoMultiple gene abnormalities are major drivers of tumorigenesis. NF-κB p65 overactivation and cGAS silencing are important triggers and genetic defects that accelerate tumorigenesis. However, ...
Author Correction: A new index for the outcome of focal segmental glomerulosclerosis - Scientific...
Nature· 17 hours agoCorrection to: Scientific
A DNA demethylase reduces seed size by decreasing the DNA methylation of AT-rich transposable...
Nature· 4 days agoA study on a soybean DNA demethylase reveals that seed size is negatively regulated by GmDMEa, which is closely linked to methylation on transposon elements.