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Multidrug-resistant Escherichia coli causing canine pyometra and urinary tract infections are...
Nature· 4 hours agoDespite extensive characterisation of uropathogenic Escherichia coli (UPEC) causing urinary tract infections (UTIs), the genetic background of non-urinary extraintestinal pathogenic E. coli ...
Flicker electroretinogram in preterm infants - Eye
Nature· 1 day agoInfants born prematurely are at risk of developing retinopathy of prematurity, which is associated with abnormalities in retinal function as measured using electroretinography. The aim of this ...
Lab-grown sperm and eggs: ‘epigenetic’ reset in human cells paves the way
Nature· 3 days agoTechnique wipes away tags on DNA that must be reprogrammed during development of reproductive cells.
Software tools identify forgotten genes
Nature· 4 hours agoFind My Understudied Genes and the Unknome database highlight interesting genes that have been neglected by science.
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury - Communications...
Nature· 1 day agoActivation of the Nrf2/HO-1 antioxidant signaling pathway exacerbates cholestatic liver injury due to excessive accumulation of bilirubin, rather than exerting a protective effect as in non-cholestatic liver injury.
Induced dual-target rebalance simultaneously enhances efficient therapeutical efficacy in tumors -...
Nature· 1 day agoMultiple gene abnormalities are major drivers of tumorigenesis. NF-κB p65 overactivation and cGAS silencing are important triggers and genetic defects that accelerate tumorigenesis. However, ...
Author Correction: Optimized model architectures for deep learning on genomic data - Communications...
Nature· 1 day agoCorrection to: Communications
Instability could explain the Sun’s curious cycle
Nature· 2 days agoThe solar magnetic field could be driven by a near-surface effect.
TBC9, an essential TBC-domain protein, regulates early vesicular transport and IMC formation in...
Nature· 6 days agoA study suggests that TBC9, one of the Rab GTPase Activating Proteins, is crucial for early vesicular transport and inner membrane complex formation by regulating Rab2, Rab11A and Rab11B in Toxoplasma gondii.
A DNA demethylase reduces seed size by decreasing the DNA methylation of AT-rich transposable...
Nature· 3 days agoA study on a soybean DNA demethylase reveals that seed size is negatively regulated by GmDMEa, which is closely linked to methylation on transposon elements.
