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... Drug Discovery Therapeutics using Artificial Intelligence (AI) and Life Science-Related Machine...
JD Supra· 1 day agoMany life science companies are using AI/ML to identify new disease targets and new therapeutics, predict the efficacy and toxicity of potential clinical therapeutic candidates ...
Structural basis of tolvaptan binding to the vasopressin V2 receptor - Acta Pharmacologica Sinica
Nature· 2 days agoOverall, the binding process consists of two stages. Tolvaptan binds initially to extracellular loops 2 and 3 (ECL2/3) before overcoming an energy barrier to enter the pocket. Our simulations ...
dsRNA formation leads to preferential nuclear export and gene expression - Nature
Nature· 3 days agoAntisense RNAs boost gene expression by accelerating the export of mRNA from the nucleus to the cytoplasm through the Dbp2-mediated formation of double-stranded RNAs, which might explain the prevalence of antisense RNAs.
New York Yankees Schedule, Live Scores & Results - MLB 2022
Covers.com· 2 days agoStay Up-To-Date With The Latest New York Yankees Schedule, Live Scores, And Results For The 2022 MLB Season!
The 7 Best Foods Naturally High in Melatonin, Recommended by Dietitians
Eating Well via Yahoo News· 6 days agoCAITLIN BENSEL/ROBBY LOZANO Certain foods and drinks naturally contain melatonin, which is measured...
Quantifying DNA replication speeds in single cells by scEdU-seq - Nature Methods
Nature· 5 days agoThis work describes scEdU-seq for studying replication fork speed in single cells, which enables researchers to investigate variability in replication speed along S phase and its associations with transcription and DNA damage.
Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair...
Nature· 5 days agoMissense mutations in histones can drive oncogenesis and disrupt chromatin, but the associated mechanisms for many such mutations remain poorly understood. Here, the authors show that cancer-associated ...
Philadelphia Phillies Schedule, Live Scores & Results - MLB 2021
Covers.com· 2 days agoStay Up-To-Date With The Latest Philadelphia Phillies Schedule, Live Scores, And Results For The 2021 MLB Season!
Researchers tie Lebrikizumab to sustained atopic dermatitis treatment effect
Medical Xpress· 4 days agoLebrikizumab is associated with sustained effects for moderate-to-severe atopic dermatitis for up to...
Health Benefits of Prune Juice
Health via Yahoo News· 5 days agoIn one study, adults aged 20–75 with chronic constipation were randomly assigned to consume either 54 grams (g), or about 2 ounces (oz), of prune juice...