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Decoding HIV’s Defenses: Innovative Vaccine Strategy Shows Promise
SciTechDaily· 20 hours agoResults from NIH-funded animal models will inform the development of vaccines for humans. Using...
Engineered CAR T cells repress signs and symptoms of allergic asthma in mice for a year
Medical Xpress· 6 days agoA team of molecular oncologists at Tsinghua University's State Key Laboratory of Molecular Oncology, in China, has found that engineered, long-lived and multifunctional T cells repress signs ...
Q&A: Researchers determine that a subclass of stem cells replenish platelets more rapidly
Medical Xpress· 3 hours agoMazzi: Platelets, the blood cells critical for preventing and stopping bleeding, are short-lived and in need of constant replenishment by blood-forming stem cells residing in the bone marrow ...
Affinity gaps among B cells in germinal centers drive the selection of MPER precursors - Nature ...
Nature· 4 days agoBatista, Schief and colleagues use a series of germline-targeting immunogens in knock-in mice expressing heavy chain sequences derived from the HIV broadly neutralizing antibody 10E8 to characterize ...
Vaccination induces broadly neutralizing antibody precursors to HIV gp41 - Nature Immunology
Nature· 4 days agoSchief and colleagues show that germline-targeting epitope scaffolds can elicit responses from rare broadly neutralizing antibody precursor B cells with predefined binding specificities and genetic features.
Study reveals circadian clock can be leveraged to enhance cancer immunotherapy
Medical Xpress· 6 days agoA multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock—the biological pacemaker that governs daily rhythms in physiological processes ...
Nociceptor-immune interactomes reveal insult-specific immune signatures of pain - Nature Immunology
Nature· 6 days agoWoolf and colleagues use single-cell transcriptomics to determine the gene signature of infiltrating immune cells and potential cell–cell interactions between receptors, ligands, ion channels ...
Fewer Suicides in Cancer Patients; Circadian Rhythm Boost; HIV Vaccine for Cancer?
MedPage Today· 4 days agoNews, features, and commentary about cancer-related issues
Chinese cell therapy may treat asthma long term with a single jab: study
South China Morning Post· 2 days agoCytokines are signalling proteins that help control inflammation in the body, but too many cytokines...
Scientists find 'Goldilocks' binding strength determines anti-cancer T-cell efficacy and fate
Medical Xpress· 4 days agoSt. Jude Children's Research Hospital scientists found that how tight a parental T cell grabs a cancer protein determines if its daughter cells will be anti-cancer effectors or exhausted. T ...
