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Neuroimmune interactions may help explain inflammatory pain, lead to better treatments
Medical Xpress· 2 hours agoResearchers have just taken the most fine-grained look to date at inflammatory pain: increased...
The PASC microbiome - Nature Immunology
Nature· 2 days agoDiagnostic tools or biomarkers for the heterogenous post-acute COVID-19 syndrome (PASC; also known as long COVID) are needed. Research now published in Cell Host and Microbe shows that the gut ...
Vaccination induces broadly neutralizing antibody precursors to HIV gp41 - Nature Immunology
Nature· 6 days agoSchief and colleagues show that germline-targeting epitope scaffolds can elicit responses from rare broadly neutralizing antibody precursor B cells with predefined binding specificities and genetic features.
Scientists find 'Goldilocks' binding strength determines anti-cancer T-cell efficacy and fate
Medical Xpress· 6 days agoThe findings, which have broad implications for improving immunotherapy, were published today in Nature Immunology. T cells are the primary anti-cancer ...
Sex differences are skin deep - Nature Immunology
Nature· 2 days agoSex differences in the prevalence of cancer and autoimmunity and susceptibility to infectious disease have long been observed, but the underlying mechanisms responsible have remained unclear ...
Affinity gaps among B cells in germinal centers drive the selection of MPER precursors - Nature ...
Nature· 6 days agoBatista, Schief and colleagues use a series of germline-targeting immunogens in knock-in mice expressing heavy chain sequences derived from the HIV broadly neutralizing antibody 10E8 to characterize ...
Novel vaccine concept generates immune responses that could produce multiple types of HIV...
Medical Xpress· 6 days agoThe findings, published today in Nature Immunology, are an encouraging, incremental step in...
Fewer Suicides in Cancer Patients; Circadian Rhythm Boost; HIV Vaccine for Cancer?
MedPage Today· 6 days agoNews, features, and commentary about cancer-related issues
Genetic changes identified as key to childhood lupus
Medical Xpress· 2 days agoIn people with lupus the body's immune system mistakenly attacks its own cells and tissues. Until now, its exact cause has been unknown, but it was thought to be a combination of genetic and ...
Q&A: Researchers determine that a subclass of stem cells replenish platelets more rapidly
Medical Xpress· 2 days agoMazzi: Platelets, the blood cells critical for preventing and stopping bleeding, are short-lived and in need of constant replenishment by blood-forming stem cells residing in the bone marrow ...