Search results
Oncofetal SNRPE promotes HCC tumorigenesis by regulating the FGFR4 expression through alternative...
Nature· 12 hours agoDue to insufficient knowledge about key molecular events, Hepatocellular carcinoma (HCC) lacks effective treatment targets. Spliceosome-related genes were significantly altered in HCC. Oncofetal ...
Higher surface folding of the human premotor cortex is associated with better long-term learning...
Nature· 12 hours agoA brain imaging study shows that humans with more complex cortical folds in a premotor brain region have a higher capacity to learn a challenging new motor skill during six weeks of practice.
Rosacea is strongly associated with melanoma in Caucasians - Scientific Reports
Nature· 12 hours agoRosacea is often considered a cosmetic problem but is known to be associated with a variety of comorbidities. To identify such risks, we generated two age- and sex-matched real-world cohorts ...
Bio-stimulating effect of endophytic Aspergillus flavus AUMC 16068 and its respective...
Nature· 12 hours agoHeavy metal accumulation is one of the major agronomic challenges that has seriously threatened food safety. As a result, metal-induced phytotoxicity concerns require quick and urgent action ...
In vivo cyclic overexpression of Yamanaka factors restricted to neurons reverses age-associated...
Nature· 2 days agoPartially reprogramming a specific population of neurons in the cerebral cortex of mice, improves cognition through greater activation in memory circuits and plasticity induced by the reorganization of the extracellular matrix.
KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid...
Nature· 2 days agoInactivated suppressor of mothers against decapentaplegic homolog (SMAD) 4 significantly affects cancer development in pancreatic ductal adenocarcinoma (PDAC). However, the contribution of smad4 ...
Neurophysiological avenues to better conceptualizing adaptive cognition - Communications Biology
Nature· 2 days agoThis article explores novel routes to better analyze neural processes underlying the brain’s adaptability and cognitive functioning, focusing on executive functions and cognitive control. It ...
Phosphorylation of caspase-8 by RSKs via organ-constrained effects controls the sensitivity to...
Nature· 2 days agoCaspase-8 (Casp8) serves as an initiator of apoptosis or a suppressor of necroptosis in context-dependent manner. Members of the p90 RSK family can phosphorylate caspase-8 at threonine-265 ( ...
A DNA demethylase reduces seed size by decreasing the DNA methylation of AT-rich transposable...
Nature· 5 days agoA study on a soybean DNA demethylase reveals that seed size is negatively regulated by GmDMEa, which is closely linked to methylation on transposon elements.
Palladium doped PDA-coated hercynite as a highly efficient catalyst for mild hydrogenation of...
Nature· 12 hours agoHercynite magnetic nanoparticles were produced through the co-precipitation of ferrous and aluminum cations. The surface of hercynite was respectively coated with silica, 2,4,6-trichloro-1,3,5 ...