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Cancer drug shows powerful anti-tumor activity in animal models of several different tumor types
Medical Xpress· 7 days agoThe drug has shown powerful anti-tumor activity in animal models of several different tumor types, including ovarian cancer and an aggressive form of breast
Breast cancer ‘immunity’ for survivors could be achieved by killing ‘undruggable’ cells
Daily Telegraph· 5 days agoAround 10 per cent of survivors will suffer a relapse, but this increases to 40 per cent among...
PKMYT1, a potential 'Achilles heel' of treatment resistant ER+ breast cancers with the poorest...
Medical Xpress· 4 days agoLooking to identify new vulnerabilities in this type of cancer that could lead to improved...
Seattle researchers explore causes of ovarian cancer: HealthLink
KING5 Seattle· 4 days agoMedical researchers in Washington state are looking deeper into what causes ovarian cancer, thanks...
Mirat Shah, MD, on Elacestrant's FDA Approval for Breast Cancer With ESR1 Mutations
MedPage Today· 7 days agoFDA scientists published a detailed rationale for the approval of elacestrant (Orserdu), the first...
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous...
Nature· 4 days agoThis induced HRR malfunction probably leads to the synthetic lethality of tumor cells with homologous recombination deficiency (HRD). Furthermore, E7820, in combination with olaparib, exerted ...
Multi-wall carbon Nanotube surface-based functional nanoparticles for stimuli-responsive dual...
Nature· 1 day agoStudies on cell lines have shown that the combination of curcumin and MTX with CNT can increase and improve the effectiveness of both drugs against cancer
Anti-Cancer Drug Pembrolizumab: Frequently Used Alone Or With Other Treatments
Forbes· 1 day agoPembrolizumab, sold as Keytruda by Merck & Co., was one of the first inhibitors to hit the market. A...
Nuclear receptors — studying genes to understand hormones - Nature Reviews Genetics
Nature· 6 days agoLigand-bound receptors undergo conformational changes to facilitate binding both to DNA and to co-factors that facilitate interactions with chromatin and core transcriptional machinery to activate ...
Eisai Showcases Oncology Portfolio and Pipeline at ASCO 2024
FOX 23 News Albany· 5 days agoEisai announced today the presentation of research across multiple types of cancer from its oncology portfolio and pipeline during the 2024 American Society of Clinical Oncology ...