Converting CO2 to formic acid by tuning quantum states in metal chalcogenide clusters -...
Nature· 1 hour agoFinding an efficient catalyst to convert CO2 into useful products is a challenging problem. Here, the authors use first-principles calculations to show how the attached donor/acceptor ligands ...
JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial...
Nature· 3 days agoPulmonary arterial hypertension (PAH) is a chronic disorder characterized by hyperproliferation of pulmonary arterial smooth muscle cells (PASMCs). JMJD1C, a member of the Jumonji domain containing ...
Synthetic maize centromeres transmit chromosomes across generations - Nature Plants
Nature· 5 days agoDawe et al. report a protein tethering method for recruiting Centromeric Histone H3 to synthetic repeat arrays. Newly recruited Centromeric Histone H3 organized ...
Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic...
Nature· 6 days agoAntimicrobial protein REG3A improved insulin sensitivity by combating oxidative stress and activating AMPK in skeletal muscle in HFD-induced obese mice overexpressing human REG3A in the liver.
Exhausted intratumoral Vδ2− γδ T cells in human kidney cancer retain effector function - Nature...
Nature· 5 days agoγδ T cells contribute to cancer immunity by killing tumor cells, but their function in the context of immune checkpoint inhibition is less clear. Here the authors show that a V</ ...
Inflammatory stimuli induce shedding of heparan sulfate from arterial but not venous porcine...
Nature· 3 days agoEndothelial dysfunction is an early event of vascular injury defined by a proinflammatory and procoagulant endothelial cell (EC) phenotype. Although endothelial glycocalyx disruption is associated ...
Inhibition of ERK1/2 signaling prevents bone marrow fibrosis by reducing osteopontin plasma levels...
Nature· 5 days agoClonal myeloproliferation and development of bone marrow (BM) fibrosis are the major pathogenetic events in myelofibrosis (MF). The identification of novel antifibrotic strategies is of utmost ...
Systematic analysis of prophage elements in actinobacterial genomes reveals a remarkable...
Nature· 4 days agoActinobacteria represent one of the largest bacterial phyla harboring many species of high medical, biotechnological and ecological relevance. Prophage elements are major contributors to bacterial ...
Elucidating the reaction mechanism of a palladium-palladium dual catalytic process through kinetic...
Nature· 3 days agoSynergistic bimetallic catalysis has been proposed to be an alternative mechanism of palladium catalysed cross-coupling reactions, however, little is known about the details of this postulated ...
Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice...
Nature· 7 days agoKnockout of Mir125b-2 in mice leads to defects in hippocampus-related behaviors and affects hippocampal expression of Grin2a and NMDAR-mediated currents.
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