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KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid...
Nature· 3 days agoHowever, the contribution of smad4 loss to drug resistance in PDAC is largely undetermined. In the present study, we reported that the loss of SMAD4 endows PDAC cells the ...
$1.031 million Madeira home sale among the week's top property transfers
Cincinnati.com | The Enquirer via Yahoo Finance· 2 days ago...Christina Marie; $460,000 7232 Creekview Dr: Ditullio Dan to Lipps Faith K & Kaleb M Rutherford;...
Inter move into Oaktree era as Scudetto parade ends at Verona
AFP via Yahoo Sports· 5 days ago...Milan end their triumphant Serie A season at Verona on Sunday night in a state of limbo after the...
Phosphorylation of caspase-8 by RSKs via organ-constrained effects controls the sensitivity to...
Nature· 3 days agoMutating T265 in caspase-8 to alanine (A) in mice blocked TNF-induced necroptotic cecum damage but resulted in unexpectedly massive injury in the small intestine. Here, we ...
Joe Joyce vs Derek Chisora: Heavyweights to fight in London in July
BBC News· 4 days agoJoe Joyce will face British heavyweight rival Derek Chisora on 27 July in London. Joyce, 38, is in...
p52-ZER6/IGF1R axis maintains cancer stem cell population to promote cancer progression by enhancing...
Nature· 6 days agoZER6 is a zinc-finger protein with two isoforms possessing different amino termini: p52-ZER6 and p71-ZER6. Since their discovery, almost no study reported on their biological and pathological ...
Melatonin alleviates septic ARDS by inhibiting NCOA4-mediated ferritinophagy in alveolar macrophages...
Nature· 3 days agoFerroptosis is a novel form of programmed cell death which can exacerbate lung injury in septic acute respiratory distress syndrome (ARDS). Alveolar macrophages, crucial innate immune cells, ...
Key node identification for a network topology using hierarchical comprehensive importance...
Nature· 3 hours agoThe identification of key nodes in complex networks has always been a hot topic in network scientific research1,2. The stability of the network topology determines the performance of the entire ...
MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy - Cell Death &...
Nature· 4 days agoEmerging evidence suggests that MLKL plays a key role in liver disease. However, how MLKL contributes to hepatocarcinogenesis has not been fully elucidated. Herein, we report ...
2024 French Open Women’s Seed Report: Predicting an Iga Świątek Three-Peat
Sports Illustrated· 4 days agoThe reigning Roland Garros champion leads a stacked women’s draw, which also features rivals Aryna...