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A genome-wide association study identifies a locus associated with knee extension strength in older...
Nature· 2 days agoA genome-wide association study on knee extension strength in 3452 persons of Japanese ancestry 60 years old and above identifies a significant association at a single locus that includes TACC2, a gene encoding a cytoskeleton-related protein.
Inhibiting proBDNF to mature BDNF conversion leads to ASD-like phenotypes in vivo - Molecular...
Nature· 4 days agoAutism Spectrum Disorders (ASD) comprise a range of early age-onset neurodevelopment disorders with genetic heterogeneity. Most ASD related genes are involved in synaptic function, which is ...
Genome-wide association analysis uncovers rice blast resistance alleles of Ptr and Pia -...
Nature· 2 days agoA GWAS on 500 genetically diverse rice accessions enables identification of an allelic series for the unusual Ptr rice blast resistance gene, and the Pia resistance locus.
Melanophilin regulates dendritogenesis in melanocytes for feather pigmentation - Communications...
Nature· 5 days agoThis study presents the essential functions of the ZnF motif in sorting of the melanophilin protein and novel functions of melanophilin in dendritogenesis in melanocytes.
Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model...
Nature· 2 days agoQUINT workflow analysis of cell and amyloid density in AD-BXD mice demonstrates age-dependent and strain-specific increases in gliosis and amyloid accumulation. These changes in brain composition influence age-related variations in gene expression.
A ResNet mini architecture for brain age prediction - Scientific Reports
Nature· 6 days agoThe brain presents age-related structural and functional changes in the human life, with different extends between subjects and groups. Brain age prediction can be used to evaluate the development ...
Construction of TiO2/WO3/TiO2 double heterojunction films for excellent electrochromic performance -...
Nature· 2 days agoElectrochromic devices are applied extensively to camouflages, smart windows, heat insulation layers, and automobile rearview mirrors, etc. The amorphous WO3 is a very attractive electrochromic ...
Chromatin modifications integrate cis genomic context to instruct transcriptional outputs - Nature...
Nature· 2 days agoBy developing a modular system for precision epigenome editing, we were able to delineate the causal and quantitative role of chromatin modifications in transcription regulation. The precise ...
Roles of long noncoding RNAs in human inflammatory diseases - Cell Death Discovery
Nature· 7 days agoChemokines, cytokines, and inflammatory cells mediate the onset and progression of many diseases through the induction of an inflammatory response. LncRNAs have emerged as important regulators ...
Author Correction: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via...
Nature· 4 days agoCorrection to: Communications