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Cubic millimetre of brain mapped in spectacular detail
Nature· 22 hours agoGoogle scientists have modelled a fragment of the human brain at nanoscale resolution, revealing...
Estimating neutrosophic finite median employing robust measures of the auxiliary variable -...
Nature· 6 days agoOur study explores neutrosophic statistics, an extension of classical and fuzzy statistics, to address the challenges of data uncertainty. By leveraging accurate measurements of an auxiliary ...
Subaerial weathering drove stabilization of continents - Nature
Nature· 2 days agoThe geological histories of Archaean regions indicate that stabilization of the Earth’s continents and the formation of cratons was driven by continental emergence and subaerial weathering.
The US Congress is taking on AI —this computer scientist is helping
Nature· 22 hours agoKiri Wagstaff, who temporarily shelved her academic career to provide advice on federal AI...
Anterior cingulate cortex-related functional hyperconnectivity underlies sensory hypersensitivity in...
Nature· 6 days agoSensory abnormalities are observed in ~90% of individuals with autism spectrum disorders (ASD), but the underlying mechanisms are poorly understood. GluN2B, an NMDA receptor subunit that regulates ...
Targeting CXCR4 impaired T regulatory function through PTEN in renal cancer patients - British...
Nature· 6 days agoTregs trafficking is controlled by CXCR4. In Renal Cell Carcinoma (RCC), the effect of the new CXCR4 antagonist, R54, was explored in peripheral blood (PB)-Tregs isolated from primary RCC patients ...
US TikTok ban: how the looming restriction is affecting scientists on the app
Nature· 22 hours agoNature talks to researchers about what is at stake if users in the country lose access.
Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF -...
Nature· 3 days agoThis study identifies a unique “internal-PDZ binding motif” (IPM) of WGEF that mediates its interaction with Dvl2PDZ, leading to the release of GEF from its autoinhibitory state. It further unravels the underlying mutual Dvl2-IPM recognition aspects.
Hyperthyroidism-driven bone loss depends on BMP receptor Bmpr1a expression in osteoblasts -...
Nature· 2 days agoComparison of the bone phenotypes of hyperthyroid versus euthyroid bone cell-specific conditional knockout mice suggests that the osteoblastic, but not osteoclast, BMP receptor BMPR1A is a main driver of hyperthyroidism-associated bone disease.
Major AlphaFold upgrade offers boost for drug discovery
Nature· 2 days agoLatest version of the AI models how proteins interact with other molecules — but DeepMind restricts...