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10 signs you might have celiac disease or gluten sensitivity
WFLA· 5 days agoTAMPA (BLOOM) – Ever heard of celiac disease or gluten sensitivity and wondered, “Could that be me?”...
BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation -...
Nature· 4 days agoThe N-BAR domain protein BIN1 acts as a scaffolding protein during filopodia formation in myoblast cells, together with identified co-factors.
Common cold viruses circulating in children threaten wild chimpanzees through asymptomatic adult...
Nature· 6 days agoReverse zoonotic respiratory diseases threaten great apes across Sub-Saharan Africa. Studies of wild chimpanzees have identified the causative agents of most respiratory disease outbreaks as ...
Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression - Communications...
Nature· 6 days agoPNUTS-deficient mice exhibit multiorgan failure and vascular leakage. PNUTS regulates SEMA3B, suggesting a target for endothelial aging.
How men evolved to care for babies — before society got in the way
Nature· 6 hours agoAn exploration of the evolution of male nurturing shows why, unlike fathers among other great apes,...
Coinfection frequency in water flea populations is a mere reflection of parasite diversity -...
Nature· 2 days agoA field study of coinfection prevalence in water fleas populations revealed strong temporal pattern with prevalence level that don’t differ from random chance, suggests that coinfections in these populations governed by parasite diversity.
Fluorescence imaging sheds light on the immune evasion mechanisms of hepatic stellate cells mediated...
Nature· 3 days agoUsing two-photon fluorescence imaging, the authors show that superoxide anion in hepatic stellate cells impairs the infiltration of CD8+ T cells in a mouse model of hepatocellular carcinoma.
Ventral subiculum promotes wakefulness through several pathways in male mice -...
Nature· 2 days agoThe ventral subiculum (vSUB), the major output structure of the hippocampal formation, regulates motivation, stress integration, and anxiety-like behaviors that rely on heightened arousal. However ...
Testing functional anchor groups for the efficient immobilization of molecular catalysts on silver...
Nature· 3 days agoThiolate groups are promising anchors to immobilize catalysts, particularly on coinage metal surfaces, but the anchor group’s impact on the local adsorption configuration of the catalyst is ...
Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF -...
Nature· 6 days agoThis study identifies a unique “internal-PDZ binding motif” (IPM) of WGEF that mediates its interaction with Dvl2PDZ, leading to the release of GEF from its autoinhibitory state. It further unravels the underlying mutual Dvl2-IPM recognition aspects.