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A meshless computational framework for studying cold spray additive manufacturing including large...
Nature· 4 days agoCold spray (CS) has emerged as an appealing additive manufacturing (AM) technique for producing or repairing individual components or entire structures. Compared to fusion-based AM technologies ...
A genome-wide association study identifies a locus associated with knee extension strength in older...
Nature· 2 days agoA genome-wide association study on knee extension strength in 3452 persons of Japanese ancestry 60 years old and above identifies a significant association at a single locus that includes TACC2, a gene encoding a cytoskeleton-related protein.
Asymmetric vibrations in the organ of Corti by outer hair cells measured from excised gerbil cochlea...
Nature· 4 days agoWe analyzed the organ of Corti motions, component by component. Outer hair cells exploit their supporting cells to boost vibrations of the upper part of the organ of Corti while minimally disturbing the basilar membrane.
Deficiency of ADAR2 ameliorates metabolic-associated fatty liver disease via AMPK signaling pathways...
Nature· 5 days agoADAR2 KO mice are protected against several HFD–induced metabolic defects, show reduced hepatic lipid accumulation, improved hepatic insulin signaling, and increased pyruvate tolerance and glycogen synthesis, by activation of AMPK signaling pathways.
Pig-organ transplants: what three human recipients have taught scientists
Nature· 6 days agoAs researchers mark the loss of the first living recipient of a pig kidney, they share what they’ve...
Melanophilin regulates dendritogenesis in melanocytes for feather pigmentation - Communications...
Nature· 5 days agoThis study presents the essential functions of the ZnF motif in sorting of the melanophilin protein and novel functions of melanophilin in dendritogenesis in melanocytes.
Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model...
Nature· 2 days agoQUINT workflow analysis of cell and amyloid density in AD-BXD mice demonstrates age-dependent and strain-specific increases in gliosis and amyloid accumulation. These changes in brain composition influence age-related variations in gene expression.
Preservation of Bacillus subtilis’ cellular liquid state at deep sub-zero temperatures in...
Nature· 6 days agoA differential scanning calorimetry study of Bacillus subtilis vitrification shows that perchlorate salts can lower the onset of intracellular vitrification, with implications for the low temperature limit of life in salt-rich subzero environments.
A ResNet mini architecture for brain age prediction - Scientific Reports
Nature· 6 days agoThe brain presents age-related structural and functional changes in the human life, with different extends between subjects and groups. Brain age prediction can be used to evaluate the development ...
Fibroblasts’ secretome from calcified and non-calcified dermis in Pseudoxanthoma elasticum...
Nature· 6 days agoAn in vitro study on fibroblasts from clinically affected or unaffected skin of patients with Pseudoxanthoma elasticum indicates that local microenvironment guides the level of matrix remodeling and the extent of elastic fiber calcification.