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Single cell RNA analysis uncovers the cell differentiation and functionalization for air breathing...
Nature· 8 hours agoSingle-cell atlas of Microhyla fissipes lungs reveals cell differentiation and functionalization during metamorphosis, further cross-species comparison sheds light vertebrate lung cell type evolution.
Open questions on carbonaceous matter in meteorites - Communications Chemistry
Nature· 1 day agoExtraterrestrial carbon gives insights into the origin of life and processes that took place billions of years ago in our solar system. Here, the authors provide an overview of what is known and of unanswered questions with a meteoritical focus.
Reduced precipitation can induce ecosystem regime shifts in lakes by increasing internal nutrient...
Nature· 10 hours agoEutrophication is a main threat to continental aquatic ecosystems. Prevention and amelioration actions have been taken under the assumption of a stable climate, which needs reconsideration.
Measuring the forces that shape early human embryos
Nature· 15 hours agoHow the cells of early human embryos pull themselves together: the strong ones exclude the weak.
Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel...
Nature· 1 day agoCerebral small vessel disease (cSVD) is a leading cause of stroke and dementia. Genetic risk loci for white matter hyperintensities (WMH), the most common MRI-marker of cSVD in older age, were ...
Unlocking bacterial potential to reduce farmland N2O emissions - Nature
Nature· 1 day agoA study presents a method to mitigate emissions of nitrous oxide from farmland using bacteria to consume nitrous oxide in soil with organic waste as a substrate and vector.
Transgene removal using an in cis programmed homing endonuclease via single-strand annealing in the...
Nature· 1 day agoThis study demonstrates that inserted transgene sequences in the Aedes aegypti genome can be pre-programmed to remove themselves and restore a formerly disrupted target gene through the in cis activity of homing endonucleases.
Upregulation of rate-limiting enzymes in cholesterol metabolism by PKCĪ“ mediates endothelial...
Nature· 1 day agoDiabetic foot ulcer (DFU) is a prevalent complication of diabetes that poses significant challenges in terms of treatment and management. It is characterized by heightened endothelial apoptosis ...
Autistic people three times more likely to develop Parkinson's-like symptoms
Nature· 3 days agoLargest study of its kind also finds increased risk in older adults with a range of intellectual...
DRAIC mediates hnRNPA2B1 stability and m6A-modified IGF1R instability to inhibit tumor progression -...
Nature· 1 day agoType 1 insulin-like growth factor receptor (IGF1R) plays an important role in cancer, however, posttranscriptional regulation such as N6-methyladenosine (m6A) of IGF1R remains unclear. Here, ...