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A disinhibitory microcircuit of the orbitofrontal cortex mediates cocaine preference in mice -...
Nature· 3 days agoBoth clinical and animal studies showed that the impaired functions of the orbitofrontal cortex (OFC) underlie the compulsive drug-seeking behavior of drug addiction. However, the functional ...
Mitochondrial transfer mediates endothelial cell engraftment through mitophagy - Nature
Nature· 4 days agoUnder stressful conditions, mesenchymal stromal cells transfer mitochondria to endothelial cells through tunnelling nanotubes, and artificially transplanting mitochondria into endothelial cells ...
3D genomic mapping reveals multifocality of human pancreatic precancers - Nature
Nature· 4 days agoQuantitative multimodal 3D reconstruction of human pancreatic tissue at single-cell resolution reveals a high burden of multifocal, genetically heterogeneous pancreatic intraepithelial neoplasias in the normal adult pancreas.
iJAZ-based approach to engineer lepidopteran pest resistance in multiple crop species - Nature...
Nature· 6 days agoIn this study, Mo et al. describe a novel biotechnological strategy to produce crop plants resistant to lepidopteran pests.
Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies - Cell...
Nature· 3 days agoForkhead box protein M1 (FOXM1) is often overexpressed in human cancers and strongly associated with therapy resistance and less good patient survival. The chemotherapy options for patients ...
Sex and gender discussions don't need to be toxic
Nature· 4 days agoThe science of sex and gender is too often misinterpreted and weaponized. Now, three experts cut through the misinformation in search of a positive...
Climate-targets group should rescind its endorsement of carbon offsets
Nature· 5 days agoLetter to the Editor
‘ChatGPT for CRISPR’ creates new gene-editing tools
Nature· 6 days agoSome of the AI-designed gene editors could be more versatile than those found in nature.
Controversial virus-hunting scientist skewered at US COVID-origins hearing
Nature· 4 days agoLawmakers interrogated Peter Daszak over his ties to China and whether his organisation, EcoHealth...
Allen J. Bard obituary: electrochemist whose techniques underpin clinical diagnostics, materials...
Nature· 4 days agoInnovator who pioneered scanning electrochemical microscopy, bioassays and solar fuels.